Research
Services
MedTech Rapid Prototyping
for Microfabrication and
Microfluidics
MedTech Rapid Prototyping for Microfabrication and Microfluidics
C-CAMP’s NBM (National Biopharma Mission of DBT-BIRAC) funded MedTech μFab with its one-stop ‘Design to Manufacture’ approach offers design, technological expertise and cutting-edge infrastructure for transforming an innovative idea in biomedical technologies into a marketable product.
In light of the 2023 National Medical Devices Policy that envisions the sector to grow from 11 Bn USD to 50 Bn USD in coming 5 years, this world-class C-CAMP facility can help realise this vision by accelerating breakthrough innovation in microfluidics and medical devices, including but not limited to in-vitro diagnostics, lab-on-a-chip among others and enabling faster commercialisation. The facility is compliant with ISO 13485:2016 standards for ‘Providing Design, Prototyping, Production and Verification Services of Medical Devices & In-Vitro Diagnostic Devices’.
The MedTech Process and Services
Idea
Innovators can walk in with their ideas or if the idea is still fluid, they can utilise C-CAMP’s immersion programmes and meetings with experts to finetune their ideas.
DESIGN
In collaboration with Dassault Systemes SolidWorks, C-CAMP has set up a Design Studio to provide support for 2D & 3D designing of innovative ideas at all scales.
proof of concept
Fabricating a Proof of Concept (POC) for plastic microfluidic/medical device fabrication using CNC micromilling, 3D printing, PCB milling, laser cutting for plastics and sheet metals.
pilot-scale production
POCs can be scaled up in production volume using vacuum casting (30-50 copies) and injection moulding (1000-10000s copies).
class 10000 cleanroom
Class 10000 Cleanroom and Lateral Flow Assays can be used for sterile packaging and assembly of medical devices and IVD kits. The cleanroom houses instruments such as reagent dispenser, clamshell laminator, strip cutter, cassette roller necessary to rapidly fabricate lateral flow assay kits.
photo-lithography
Photolithography Services using a direct laser writer are available in the Class 10000 cleanroom. This eliminates the need for an expensive photomask and can pattern microfluidic structures as small as 5 microns.
device testing
Device Testing and Characterisation using optical profilometer, fluid flow controllers, high-speed camera integrated with fluorescence microscopes, electronics and programming, NI LabVIEW automation, spectrum analyser, oscilloscopes, Universal Testing Machine.
Salient projects supported by the facility
Salient projects supported by the facility
-> Pocket Medical Scanner (Rajesh Laboratories)
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It is a non-invasive medical diagnostic device based on audiometric analysis, which has the potential to diagnose/screen multiple diseases like respiratory diseases (TB, Pneumonia), cardiovascular diseases (Pericardial effusion), etc.
-> Bio-Engineered Liver (Ykrita Life Sciences)
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Development of a bioengineered artificial ectopic liver device. This novel medical device aids the rejuvenation of an injured liver, improves survival window before transplants.
-> Optofluidic Flow Cytometer (DIA and IIT-Madras)
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The novel microfluidic chip-based platform allows for optical sensing of biological samples without the expensive open space, bulky optical components routinely used in microscopy and flow cytometry-based techniques.
-> Digital Stethoscope (AaboOne) (1008 Digital Health Pvt Ltd)
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AI Powered Smart Stethoscope for hearing, recording, and analysing heart and lung sounds for predictive and early diagnosis of ailments.
-> Microsampling and Storage Device (Benetize Pvt. Ltd)
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Development of a new micro sampling technique which uses finger prick blood to collect, store and transport blood specimens for investigations to far away hospitals.
-> Micromachined Microfluidic chips (Norwegian University of Science and Technology (NTNU), Trondheim, Norway)
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The facility fabricated 64 microfluidic chips on PMMA substrate through micromachining. The chips will help plant biology scientists understand how roots propagate towards various stimuli. With this project, the facility has expanded its footprint beyond India and is currently serving international customers.
Impact
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Since its inception, the MedTech facility has served 70+ clients across academia, start-ups, hospitals, government institutions, and corporate entities, and delivered 170+ projects successfully. In its efforts to support the scientific community and innovation ecosystem in India, the facility regularly conducts training programmes throughout the year on various aspects of microfluidics and medical devices that attracts participants from across the country.
Currently accessible equipment include
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-> Workstations with Clewin Layout Software
-> Workstations with Dassault Systemés Solidworks Software
-> PCB Milling Machine
-> Vacuum convection oven (Upto 250C
-> Metal Plasma Cutter
-> Laser cutter (1300mm x 900mm bed)
-> Workstations with NI DAQ systems
-> Digital Storage Oscilloscope (100 MHz)
-> Mixed Signal Oscilloscope (100 MHz)
-> Arbitrary Function Generator
-> DC power supply (0-30v, 0-5A)
-> Class 10000 Cleanroom
-> CNC Micromilling Machine
-> Hot Roll Laminator
-> 3D Printers (FDM & SLA)
-> Vinyl Cutter
-> Desktop Injection Molding System
-> Vacuum Casting System
-> Hot Embossing System
-> Ultrasonic Welding Machine
-> Spin Coater
-> Direct Laser Writer for Photolithography
-> LFA Printing Set-up
-> Optical Profilometer
-> Inverted and Upright Microscopy Platform
Listed are the Microfluidic Device Testing capabilities at the Facility
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Device Dimensions
-> Dektak Stylus Profiler
-> Optical Profiler (available soon)
Fluid Flow
-> Syringe Pumps
-> Pressure Pumps
-> Piezoelectric Peristaltic Pumps
Imaging
-> Inverted Fluorescence Microscope
-> Upright Fluorescence Microscope
-> Fast Imaging TDI Camera
Electronic Testing
-> NI LabView and DAQ Boards
-> Oscilloscopes
-> Mixed Signal Oscilloscope
-> DC Power Supply
-> Arbitrary Function Generator